‧ Biophysics/Drug design/Enzyme reaction
‧ Computational Chemistry/Biophysics
‧ Structural Biology/Bioinformatics
We investigate biophysical principles and structural bioinformatics in macromolecular systems. Our research interests include to (1) study the amyloid peptide aggregation mechanism and investigate the mechanisms of protein-mediated signal transduction, including allosteric effect, gating effect, ligand escape processes, ion pumps, and protein-nucleic acid interaction, (2) study charge conductivity and structural biology in biomolecular systems, (3) build biomolecules and design structural-based anti-cancer and antiviral drugs, (4) develop new computational techniques and algorithms.